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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eff6a61597b7759d9f2c98712dfdcd492ba55b6d5909d12455bedec02c692c96' 
  AND token = 'QgQ3b52P+7wSEbj3YfpMJV+WFIEEeZ9VRfEaOBDfbu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}