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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe2e4a862c50de6a1d4a99f555768ca9355e2d118a5c45563319e7ae83813037' 
  AND token = 'YP0udh7b931yCf1XZ8EHwQMxcCFcetMVx/LqLTcLuKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}