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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '919ba8da31c8e29c63012e38231c0e07c3b455908c5c8f374e1996e86b5950dd' 
  AND token = '4/tLKQFYy00yFiKtAQGYFfxPvnM1mAF5kRcc2YUOZNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}