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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '851f6d15515735557b83e8937806cd777d839e575844a9fb55b7028306a87c5a' 
  AND token = 'xqXUCKM8iopUFlsfZkHQHuSQHr63f9Kh5RULyghek70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}