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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3449c2f688224d23104e0ff2017f4325ea16990e04425f530a6f4fd1fb47557' 
  AND token = 'S9mgWYoovP1TA9hpV+8fu6dzpvSm8YCRhgco5sKdA8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}