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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b13a05194bb4dd4604d2ab8b8aab1eff4dda8cc1a8a7a9be892a3d49a97a4c65' 
  AND token = '8ul49aIN36LGjhKIM2745/5txSH4/paujKVmx7VmjQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}