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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e568c84f1b7ffa46e7701f121007b004e223d0cebd555e6cf0760e46e28e5a0' 
  AND token = '9oIJJoTJTYzsgP0fG6/rTZD5KnXYhh3/sVc8fr0Xauk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}