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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7981af1442d1be97ff2826818c2b7fedc5603c583cbbd04330f23ba55f9f99a3' 
  AND token = 'J00KbLFzF+Q1c48lk9mXQilfghxicioZ/sn9uZtRNe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}