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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d81e27ae9b3d61d45e6357296ec01729e5d750e161e986dc0bdd0c94d4bf43f' 
  AND token = 'YkKOhGnjfUus0Rs3X8+LwOIiniI3kS1z/h0nlBNTTAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}