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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36c27c6cbc94c8b746abfa457ce33a645311cbcb411fba35bec143057c805c10' 
  AND token = 'ph1W34kM1tjmIVFaxIJ2jcVMqu7XRjrXrjyEDLCnVV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}