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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e351e1c28a8788b2aeef8508670aede46798070f29660517cf7ba8f7fc36d75d' 
  AND token = 'aNb8foZoat2BClqTga2uEE2E87deostmmSv4sfPdOF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}