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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e189c1a6fff0af2cdacca30f3f5e094c654dd9801d713708f8f56dbb04fdf5f0' 
  AND token = 'v4jeIKw0WZgjlIz9OxT9VgjLaO+frWXVVxYci1RQMgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}