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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd0ffaa1a61a282735dda36541dfbdddd89a214b4fa59c389bc4c4c1da26a800' 
  AND token = 'QVXh+uz+6WGK+dTC+NbsK6X0CyxMfArRMvRQg2/5Goc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}