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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c1e2e072ec1bbd2743e7a98a44ac204e173e2eebb917f04b7bdde1fecb06a42' 
  AND token = '5s7LgZuGfAbyjq4Fw384dhpbOE6N+WAUyT5hg5U25GA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}