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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4dd902e87f755dc13f485e0b2a0e3fa6fa3a87e662128a62dd11ed6e4cff281' 
  AND token = 'B+H6+OStA3/9Pj8vYWV24HJXU2mWFMvwtpHFKPWsab8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}