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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e829304320b9628113e56b85181d20ca1a29e416db5ebe155057edb5df36012' 
  AND token = 'ZmlrPoWJWAYN4LMJ2WfHAwByh3UemcZwMz0zcsIh4pY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}