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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '396efd1f641850473cd3844c3cdc6d7ee39809da870b6aa4443303988a131a32' 
  AND token = 'XYK05Y7QJ1Xqcgpe+oEAnvih+lBnG8DyHJpSky/iIe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}