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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2516ad218fca22b0a69b211733b453bfc3773cda174dbfcfae5b208a5800bbb1' 
  AND token = 'Uze/jx5gQ13D53PMmXNW1CiZsPxbyWRoqUQuU8cbS0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}