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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a4bff99a4063720cc7dc2875e998726e75c3f0d07cd5ef9db1c23c43879be80' 
  AND token = 'pHYECkTsWFNQgROvQMfff3XfZEvbGEoW9PI+539EmFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}