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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81e86445c03668bc18cf10a22975949a39e55ff525fa91b4046a112d67f132eb' 
  AND token = 'ZJHX3My+Ie0cv90gCRo8dYm084j6IhD7j0aPcP8OTIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}