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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '848519e2b4db2d1b239571ed3e045d15ad87c19db3dc7b0147493aec41ff5521' 
  AND token = '+z4mIfyfaJuMHRTH5+1oA+5JT9dgbxGtA+FJUsCJtOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}