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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '640f6a9d65a329df23297e0b5b45951be7153598e38e0d1cc87bd68dae8dd105' 
  AND token = 'llx2V3W4Zk6ekvgV5uogC7NFUkgjXP1nqDhnVFucgHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}