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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '508640e952a423d69372f2fc320fa3f35ee054f31c4f1a10a680e3019160e7d2' 
  AND token = 'XTZ8+Qyj5YeYkJRXe4ocSV8wHfi/PdF9qOV8afPt01Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}