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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec7f6a81d681f2398c201298d22b049dd16bdf2078238c6af3b60053d1ef601b' 
  AND token = 'lqJ/Qa9m9z9JkXptSVvhjCG3S9EIKxSULMh/8ahfT64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}