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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ef60dad3f1d2907b2aad1e2bb4410636c9e9f18c63548833cab7d725926acf6' 
  AND token = 'NyOkV30uel04r1PKRysMYxhyu/6pDQ0LDB59982Zl74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}