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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b193724eb1b3c1cd247f86884889a670f3a5fe63c3aeb54e33a193b4ba9146c' 
  AND token = 'auVRMu4L4z3TMN0P5996y3bqHpW3KeO/fT3rKPkxEJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}