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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f3ac1dc6e3b59497cec572f39f9590f8db1bfa48c8849a695afd580ee150656' 
  AND token = 'THQO1kX7+jmHmMtnXiabbAgMlB5dRET5uMpEmSj+E7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}