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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f145496b224f37c9bd50f724591d409d1df65034640f44516d2fda88e7ed6ca' 
  AND token = 'ZqnQxcIeBDxJ7FASKzvsnfoo7jvtLdXf1DGBVjuR75I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}