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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1f5faff618d848f0199d56a457d9f16e1fc221923f6e807be7e0f923ad90764' 
  AND token = 'jAqYaEv5lG8puhv2AGAAcnn3PMJotBYs5YcYVCmh25U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}