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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '171b42e3606b5492993b7d8d5e1328a249f854dd4d0fcc1e58b5fcc7629f36e1' 
  AND token = '9PiUikkF7l0ZEUn6Luds+h1OIyXDq84QcdpncUNmTLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}