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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd759822803281585e73e525940d13c1177cc4cf8df746ff126520dc3646dd7c9' 
  AND token = 'bu29BB/0+ekMBKtqySHRF2nD2N2jo6YoEYzj8iWntr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}