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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27e4981a5c32fec35b34f40f4653ab1b615b9f1fc1bb5c1581f9f5aed9cef577' 
  AND token = 'JagcWWsC1DvYEmVK1x6n8HPtEMBbIeX2NfneFzQ4Jsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}