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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '137e79d44c28aa0f8370c1c99d04ffea5c3d96414b957f81c7197d9f82905041' 
  AND token = '8Y735vo/1c4OWk9+jAf/uEE+tyMfm/Vj8S2QPsbn6TM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}