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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b51c348efce3d9dd519f5bb4b1360554668b07074eddbb95f05917ea89cde67b' 
  AND token = 'gy8u+jey3TC8HUIfG+NmwQtPAF9x8GGnOn0nYY+zAD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}