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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52c46a0424f39b91b37cb9a82ab2b04c402a6b1735812d4477524d105eb505e9' 
  AND token = 'Qf3XA0AxUqg9yc2NIR9k8UU7DHtaFC1oM9R3lKrB0Xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}