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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d42ad1220ce0875e761da6c3e62dc2955c8cb69a4e531e40fa3580251759600' 
  AND token = 'lkwV4T7nFLWWRwtpwfqBVg3mXPrL7/tZBgRfjGr7cMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}