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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b1763250ef9c8047679033420fc464a5513d7b0d9f805d774789429755da86a' 
  AND token = '20CEoH8i5C1jg7VSBbi59eXFji+AePmknPc6iwxj4yU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}