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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2d35267f2295ecad116102814f056722539b1c702740709e03f39612e9379d5' 
  AND token = 'FVby/ZmCL3ruBkFJo4yNm8n1s9PRb6XODnSgOgAKOWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}