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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '849e300d9f0b4ac39cce57fe582625427d7ba1566d2bc3400627c800017e4559' 
  AND token = 'kTSL+UYovojBGl9PiC7c0sNWhA4KwHx3R7occgQrEAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}