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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74b920932afe6edc71b03b92671fb444ffbd9ebf1067ec436abe263ca191a1fe' 
  AND token = 'pd7PD0C0BWD0vdUVdVEbRVIqwMQ0FRe/+bzIyrhQXqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}