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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '489d633427e69e6976c6a3a7b3243f50c87e9c6b062266f675b65a9231451719' 
  AND token = '0SMPV48d0q5/LGusOhHRIMaNl5pO0J+tlIUAZ0xofPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}