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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35549f60e1e7c8fac8931d24b29e3f05f23042d908945458854b20717c80cee1' 
  AND token = 'YVvqs0xi5T0ufkzL0PQnEFlLn+i4sxrgUUJ6FpAiHU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}