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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c359e411b968fcbdf7d7f394392fcc12dc9c4af7962a1be55b6afae37241faa4' 
  AND token = 'u9ZHqX49zBXnY1jJ3mBE2WHIf/Q/DIF1WtQkEth1k+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}