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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abe8a1957c304a5861f0ba7500a44293625a44b3725b9cbec5e2bea8a0e6a5b1' 
  AND token = '6kRbYW3/bM8xZDc3ZrmizM03mvsElpbSZoHM/G4wfzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}