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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a55c0dd0a6b46f6fbaba0f5250a67ade206dee1839b6ec6a4bde1771d721d935' 
  AND token = 'LEn53ga7n+9Wp9SIquf+NmQOUnVG5IDeXFiHo69aP3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}