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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c50d5ad1b601d068ba4eadcbb68c0ba529d5d697f16266b9c1a8356ba33c94a' 
  AND token = 'U9eQDLz1B5E+/VjGP3OaOCbNdUDO2hSU5HqEUxDOJZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}