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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9280ba4da2e73cecf3f22435905773e9c319cfa9a35f4e288eced0a22990cf1a' 
  AND token = 'AfLrsARsBcxwFtYCm0V3ttakVRVIlI1aWwlUGfdtrhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}