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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4d4f9112122c4c0f35819a0d95de9ad5c8e237982b47998e6b423f050235e44' 
  AND token = 'XmAe4KpC50du20dKpT5uPRZCJbzFU4jU6hhwFtwaZzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}