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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fad06fa76a85a792a09285d560fd8c005bc9d5b4dd47c74a4d4f4c966842a9f1' 
  AND token = 'Zj65zPQ7mCThpCUqfvMv5YhGlGphhSqAcdWAUr05fiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}