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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '387e4b20269b23402f09f305a2caa12facb3f3fdf80feea86846ae53109f9e91' 
  AND token = 'Snz5wjEzZ675AEBm0V0WQJNRzsOyUIuih3EoJ4uTjbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}